Dept. of Biochemistry & Organic Chemistry
Adolf Gogoll
| Research Interests: | Molecular tools |
| Photoswitchable peptidomimetics | |
| Organometallic Chemistry |
Characterization of small organic molecules using "molecular tools", i.e., hosts systems that can bind a target molecule, thus simplifying NMR studies of conformationally flexible species in solution.
Chiral hosts
The absolute configuration of π-allyl Ligands can be determined by complexation to chiral bispidine ligands.
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- Determination of Absolute Configuration of (π-Allyl)Palladium Complexes by NMR Spectroscopy and Stereoselective Complexation. A. Gogoll, C. Johansson, A. Axén, and H. Grennberg, Chem. Eur. J. 2001, 7, 396.
Conformational restriction
Complexation reduces the conformational flexibility Alignment of acyclic π-allyl Ligands against a chelating ligand surface.
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- Conformational Restriction of Acyclic π-Allyl Ligands in (3,7-Diphenyl-1,5-dimethylbispidinone)-(η3-alkenyl)palladium Complexes. A. Gogoll, H. Grennberg, and A. Axén, Organometallics 1998, 17, 5248.
Shift reagents: Measurement of molecular geometry
Quantify aromatic ring current effects and determine atom positions
- N,N'-Diphenylbispidinone Derivatives as a New Type of Chelating Nitrogen Ligand for Stereochemical Analysis of (π-Allyl)palladium Complexes: Complexation Studies and X-Ray Structure of (3,7-diphenyl-1,5-dimethylbispidinone)-[1,3-η3 -propenyl-palladium] trifluoro-methane sulfonate. A. Gogoll, H. Grennberg, and A. Axén, Organometallics 1997, 16, 1167.