Section of Chemistry : Dept. Biochemistry & Organic Chemistry :
Research : Enzymology and drug discovery

Helena Danielson

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Dept. of Biochemistry & Organic Chemistry

Sensorgrams NNRTI and HIV RT mutants
HIV RT NNRTI binding pocket

Former PhD Students

THESIS AND CURRENT POSITIONS

 

Omar Gutierres Arenas

Sensitivity, Noise and Detection of Enzyme Inhibition in Progress Curves (2007)

Current position: Post. Doc., University of Miami, Florida, USA

 

Thomas Gossas

Protease Activity, Inhibition and Ligand Interaction Analysis: Developments and Applications for Drug Discovery (2007)

Current position: Scientist, Beactica AB, Uppsala, Sweden

 

Dan Backman

Interaction Studies of Secreted Aspartic Proteases (Saps) from Candida albicans : Application for Drug Discovery (2005)

Current position: Post. Doc., Department of Protein Biochemistry, Institute of Organic chemistry and Biochemistry, Academy of Science, Czech Republic

 

Matthis Geitmann

Biosensor Studies of Ligand Interactions with Structurally Flexible Enzymes: Applications for Antiviral Drug Development (2005)

Current position: Scientist, Beactica AB, Uppsala, Sweden

 

Maria Lindgren

Exploring inhibitors of HIV-1 protease. Interaction studies with applications for drug discovery (2004)

Current position: Scientist, Resistentia, Uppsala, Sweden

 

Anton Poliakov

Peptide-Based Inhibitors of Hepatitis C Virus NS3 Serine Protease: Kinetic Aspects and Inhibitor Design (2004)

Current position: Post. Doc., Birmingham, Alabama, USA

 

Cynthia Shuman

Interaction Characteristics of Viral Protease Targets and Inhibitors: Perspectives for drug discovery and development of model systems (2003)

Current position: GE Healthcare/Biacore, San Diego, California, USA

 

Göran Ahlsén

Structure-activity and resistance studies of HIV-1 protease inhibitors (2000)

Current position: Post. Doc., Columbia University, New York, USA

 

Per-Olof Markgren

Analysis of the interaction between HIV-1 protease and inhibitors: Applications for drug discovery (2000)

Current position: Scientist, Astra-Zeneca, Huddinge, Sweden

 

Ulrika Nillroth

Enzymatic characterization of inhibitors of HIV-1 protease. Structure-activity and resistance studies (1996)

Current position: Roche, Stockholm, Sweden