Section of Chemistry : Dept. Biochemistry & Organic Chemistry :
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Dept. of Biochemistry & Organic Chemistry

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Publications 2001

Publications From biochemistry - 49 publications

 

Title Autor Journal/Year

P1/P1' modified HIV protease inhibitors as tools in two new sensitivesurface plasmon resonance biosensor screening assays.

Alterman, M;
Sjobom, H;
Safsten, P;
Markgren, PO;
Danielson, UH;
Hamalainen, M;
Lofas, S;
Hulten, J;
Classon, B;
Samuelsson, B;
Hallberg, A.

Eur J Pharm Sci, 2001, 13, 203

Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain.

Johansson, A;
Hubatsch, I;
Akerblom, E;
Lindeberg, G;
Winiwarter, S;
Danielson, UH;
Hallberg, A.

Bioorg Med Chem Lett , 2001, 11, 203

Mechanism of substrate inhibition in cellulose synergistic degradation

Valjamae, P;
Pettersson, G;
Johansson, G.

EUR. J. OF BIOCHEMISTRY , 2001, 16 , 4520-4526

Synthesis and comparative molecular field analysis (CoMFA) of symmetricand nonsymmetric cyclic sulfamide HIV-1 protease inhibitors.

Schaal, W;
Karlsson, A;
Ahlsen, G;
Lindberg, J;
Andersson, HO;
Danielson, UH;
Classon, B;
Unge, T;
Samuelsson, B;
Hulten, J;
Hallberg, A;
Karlen, A.

J Med Chem , 2001, 44 , 155

Solid phase synthesis of partially protected tocinoic acid: Optimization with respect to resin and protecting groups Hlavacek, J;
Ragnarsson, U.
JOURNAL OF PEPTIDE SCIENCE,
2001, 7 , 349-357

Shake-up and shake-off excitations with associated electron losses in X-ray studies of proteins

Persson, P;
Lunell, S;
Szöke, A;
Ziaja, B;
Hajdu, J.

Protein Science ,
2001, 10, 2480-2484

Role of the glutamyl alpha-carboxylate of the substrate glutathione in the catalytic mechanism of human glutathione transferase A1-1 Gustafsson, A;
Pettersson, P. L;
Grehn, L;
Jemth, P;
Mannervik, B.
Biochemistry ,
2001, 40, 15835-15845

Role of conserved local motifs in folding and stability of hGSTP1-1

Dragani, B;
Stenberg, G;
Cocco, R;
Mannervik, B;
Aceto, A.

CHEMICO-BIOLOGICAL INTERACTIONS ,
2001, 1-3, 17-18

The role of glutathione in the isomerization of Delta(5)-androstene-3,17-dione catalyzed by human glutathione transferase A1-1

Pettersson, PL;
Mannervik, B.

J. OF BIOLOGICAL CHEMISTRY,
2001, 15, 11698-11704

The dimeric state of glutathione transferases; role of a key residue at the subunit interface in human GSTP1-1

Stenberg, G;
Abdallah, AM;
Mannervik, B.
CHEMICO-BIOLOGICAL INTERACTIONS,
2001, 1-3, 24-27

A conserved 'hydrophobic staple motif' plays a crucial role in the refolding of human glutathione transferase Pl-l

Stenberg, G;
Dragani, B;
Cocco, R;
Principe, DR;
Mannervik, B;
Aceto, A.

CHEMICO-BIOLOGICAL INTERACTIONS , 2001,1-3, 49-50

Capture and analysis of low molecular weight ligands by surface plasmon resonance combined with mass spectrometry Sönksen, C. P; Roepstorff, P; Markgren, P-O;Danielson, U. H;Hämäläinen, M; Jansson, Ö. Eur. J. of Mass Spectrometry , 2001, 7,385-391
Effects of cholesterol and model transmembrane proteins on drug partitioning into lipid bilayers as analysed by immobilized-liposome chromatography Lagerquist, C;
Beigi, F;
Karlén, A;
Lennernäs, H;
Lundahl, P.
J. Pharm. Pharmacol., 2001, 53, 1477-1487
Chlorine kinetic isotope effects on the haloalkane dehalogenase reaction Lewandowicz, A;
Rudzinski, J;
Tronstad, L;
Widersten, M;
Ryberg, P;
Matsson, O;
Paneth, P.
J. OF THE AMERICAN CHEMICAL SOCIETY, 2001, 19, 4550-4555
An amperometric cellobiose dehydrogenase-based biosensor can be used for measurement of cellulase activity Hilden, L;
Eng, L;
Johansson, G;
Lindqvist, SE;
Pettersson, G.
ANALYTICAL BIOCHEMISTRY , 2001, 290, 245-250
Diamond microchips for fast chromatography of proteins Bjorkman, H;
Ericson, C;
Hjerten, S;
Hjort, K .
SENSORS AND ACTUATORS B-CHEMICAL , 2001, 1, 71-77
The folding and stability of human alpha class glutathione transferase A1-1 depend on distinct roles of a conserved N-capping box and hydrophobic staple motif Cocco, R;
Stenberg, G;
Dragani, B;
Principe, DR;
Paludi, D;
Mannervik, B;
Aceto, A.
J. OF BIOLOGICAL CHEMISTRY , 2001, 34, 32177-32183
Yeast glyoxalase I is a monomeric enzyme with two active sites Frickel, EM;
Jemth, P;
Widersten, M;
Mannervik, B.
J. OF BIOLOGICAL CHEMISTRY , 2001, 3, 1845-1849
Characterization of a peptide antibody toward hGSTA4-4 Gardner, JL;
Bammler, TK;
Mannervik, B;
Gallagher, EP.
CHEMICO-BIOLOGICAL INTERACTIONS , 2001, 1-3, 63-67
The cytochrome c domain of dimeric cytochrome cd(1) of Paracoccus pantotrophus can be produced at high levels as a monomeric holoprotein using an improved c-type cytochrome expression system in Escherichia coli Gordon, EHJ;
Steensma, E;
Ferguson, SJ .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , 2001, 3, 788-794
The structure of an alternative form of Paracoccus pantotrophus cytochrome cd(1) nitrite reductase Sjogren, T;
Hajdu, J.
J. OF BIOLOGICAL CHEMISTRY, 2001, 31, 29450-29455
Structure of the bound dioxygen species in the cytochrome oxidase reaction of cytochrome cd(1) nitrite reductase Sjogren, T;
Hajdu, J.
J. OF BIOLOGICAL CHEMISTRY , 2001, 16, 13072-13076
Heme ligation and conformational plasticity in the isolated c domain of cytochrome cd(1) nitrite reductase Steensma, E;
Gordon, E;
Oster, LM;
Ferguson, SJ;
Hajdu, J.
J. OF BIOLOGICAL CHEMISTRY , 2001, 8, 5846-5855
Disorder-to-order transition of the active site of human class Pi glutathione transferase, GST P1-1 Hitchens, TK;
Mannervik, B;
Rule, GS.
BIOCHEMISTRY, 2001, 39, 11660-11669
A highly acidic tyrosine 9 and a normally titrating tyrosine 212 contribute to the catalytic mechanism of human glutathione transferase A4-4 Hubatsch, I;
Mannervik, B.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , 2001, 3, 878-882
Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones Johansson, AS;
Mannervik, B.
J. OF BIOLOGICAL CHEMISTRY , 2001, 35,33061-33065
Ser11 plays several roles in the catalytic mechanism of rat glutathione transferase T2-2 Jemth, P;
Mannervik, B.
CHEMICO-BIOLOGICAL INTERACTIONS , 2001, 1-3, 178-181
Human glutathione transferase Al-1 demonstrates both half-of-the-sites and all-of-the-sites reactivity Lien, S;
Gustafsson, A;
Andersson, AK;
Mannervik, B.
J. OF BIOLOGICAL CHEMISTRY ., 2001, 38, 35599-35605
Structural basis for 4-hydroxyalkenal activity in human glutathione transferase A4-4 Nilsson, LO;
Gustafsson, A;
Hubatsch, I;
Mannervik, B.
CHEMICO-BIOLOGICAL INTERACTIONS , 2001, 1-3, 360-363
Improved heterologous expression of human glutathione transferase A4-4 by random silent mutagenesis of codons in the 5 ' region Nilsson, LO;
Mannervik, B .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS , 2001, 2-3 , 101-106
The isomerization of Delta(5)-androstene-3,17-dione catalyzed by human glutathione transferase A1-1 Pettersson, PL;
Mannervik, B.
CHEMICO-BIOLOGICAL INTERACTIONS , 2001, 1-3, 196-199
Evolutionary design of glutathione-linked proteins in vivo and in vitro based on sampling of modules from pre-existing structures Mannervik, B;
Bolton-Grob, R;
Cameron, AD;
Etahadieh, M;
Gustafsson, A;
Hansson, LO;
Hubatsch, I;
Jemth, P;
Johansson, AS;
Jones, TA;
Larsson, AK;
Nilsson, LO;
Olin, B;
Pettersson, PL;
Ridderstrom, M;
Stenberg, G;
Widersten, M;
Wisen, S.
CHEMICO-BIOLOGICAL INTERACTIONS , 2001, 1-3, 3-6
Determination of interaction kinetic constants for HIV-1 protease inhibitors using optical biosensor technology Markgren, PO;
Lindgren, MT;
Gertow, K;
Karlsson, R;
Hämäläinen, M;
Danielson, UH.
ANALYTICAL BIOCHEMISTRY, 2001, 2, 207-218
Proposed reductive metabolism of artemisinin by glutathione transferases in vitro Mukanganyama, S;
Naik, YS;
Widersten, M;
Mannervik, B;
Hasler, JA.
FREE RADICAL RESEARCH, 2001, 4, 427-434
Visualizing photochemical dynamics in solution through picosecond x-ray scattering - art. no. 195508 Neutze, R;
Wouts, R;
Techert, S;
Davidsson, J;
Kocsis, M;
Kirrander, A;
Schotte, F;
Wulff, N.
PHYSICAL REVIEW LETTERS , 2001, 19, 5508
Molecular dynamics simulations of ubiquinone; a survey over torsional potentials and hydrogen bonds Nilsson, JA;
Lyubartsev, A;
Eriksson, LA;
Laaksonen, A.
MOLECULAR PHYSICS, 2001, 21, 1795-1804
GROMACS 3.0: a package for molecular simulation and trajectory analysis Lindahl, E;
Hess, B;
van der Spoel, D.
J. OF MOLECULAR MODELING , 2001, 8, 306-317
Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance Olsson, U;
Egnell, AC;
Lee, MR;
Lunden, GO;
Lorentzon, M;
Salmivirta, M;
Bondjers, G;
Camejo, G.
DIABETES , 2001, 9, 2126-2132
Chromatographic retention of drug molecules on immobilised liposomes prepared from egg phospholipids and from chemically pure phospholipids Osterberg, T;
Svensson, M;
Lundahl, P.
EUR. J. OF PHARMACEUTICAL SCIENCES , 2001, 4, 427-439
Enhancing reductive cleavage of aromatic carboxamides Ragnarsson, U;
Grehn, L;
Maia, HLS;
Monteiro, LS.
ORGANIC LETTERS, 2001, 13, 2021-2023
Diffraction of partially coherent X-rays and the crystallographic phase problem Szoke, A. ACTA CRYSTALLOGRAPHICA SECTION A , 2001, 57, 586-603
B3LYP studies of the formation of neutral tyrosyl radical Y-Z(center dot) and regeneration of neutral tyrosine Y-Z in PSII Wang, YN;
Eriksson, LA.
INTERNATIONAL J. OF QUANTUM CHEMISTRY, 2001, 3-4, 220-229
A theoretical study of 5-halouracils: electron affinities, ionization potentials and dissociation of the related anions Wetmore, SD;
Boyd, RJ;
Eriksson, LA.
CHEMICAL PHYSICS LETTERS , 2001, 1-2, 151-158
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate Wilmouth, RC;
Edman, K;
Neutze, R;
Wright, PA;
Clifton, IJ;
Schneider, TR;
Schofield, CJ;
Hajdu, J.
NATURE STRUCTURAL BIOLOGY, 2001, 8, 689-394
Intterindividual variability of glutathione transferase expression Johansson, A-S;
Mannervik, B;
GM Pacifici, O; Pelkonen E.
Interindividual Variability in Human Drug Metabolism, 2001, 460-519
Glutathione transferases in the protection against ortho-quinones and other products of oxidative cellular processes Mannervik, B. Mechanisms of Degeneration and Protection of the Dopaminergic System, J. Segura-Aguilar, Ed, 2001,
Advantages of quantitative affinity chromatography for the analysis of solute interaction with membrane proteins. Lundqvist, A;
Lundahl, P.
J Biochem. Biophys. Methods, 2001, 49, 507-521
Synthetic methodology for alkyl substituted hydrazines Ragnarsson, U. CHEMICAL SOCIETY REVIEWS, 2001, 4, 205-213
Aims & Scope International Journal of Quantum Chemistry Brändas, E;
Öhrn, Y.
International Journal Of Quantum Chemistry, 2001, 3