Section of Chemistry : Dept. Biochemistry & Organic Chemistry :
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Dept. of Biochemistry & Organic Chemistry

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Publications 2002

Publications From biochemistry - 40 publications

 

Title Autor Journal/Year

Design of a monomeric human glutathione transferase GSTP1, a structurally stable but catalytically

Abdalla, A-M;
Bruns, C.M;
Tainer, J. A;
Mannervik, B;
Stenberg, G.

Protein Engineering, 2002, 15, 827-834

Resistance profiles of cyclic and linear inhibitors of HIV-1 protease

Ahlsen, G;
Hulten, J;
Shuman, CF;
Poliakov, A;
Lindgren, MT;
Alterman, M;
Samuelsson, B;
Hallberg, A;
Danielson, UH.

Antivir Chem Chemother, 2002, 13, 27-37

Spin structure function g 1(x,Q**2) and the DHGHY integral I(Q**2) at low Q**2: Predictions from the GVMD model

Badelek, B;
Kwiecinski, J;
Ziaja, B.

EUR. PHYS J. , 2002, C26 , 45-49

Theoretical Studies of the Cross-Linking Mechanisms between Cytosine and Tyrosine

Ban, F.Q;
Lundqvist, M.J;
Boyd, R.J;
Eriksson, L.A.

J. OF THE AMERICAN CHEMICAL SOCIETY , 2002, 11 , 2753-2761

The catalytic pathway of horseradish peroxidase at high resolution Berglund, GI;
Carlsson, GH;
Smith, AT;
Henriksen, A;
Hajdu, J.
NATURE,
2002, 6887 , 463-468

HIV-1 Vif-derived peptide inhibits drug-resistant HIV proteases

Blumenzweig, I;
Baraz, L;
Friedler, A;
Danielson, UH;
Gilon, C;
Steinitz, M;
Kotler, M.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ,
2002, 2, 832-842

An ensemble of Theta class glutathione transferases with novel catalytic properties generated by stochastic recombination of fragments of two mammalian enzymes Broo, K;
Larsson, A-K;
Jemth, P;
Mannervik, B.
Journal of Molecular Biology ,
2002, 318, 59-70

Conjugation of the linoleic acid oxidation product, 13-oxooctadeca- 9,11-dienoic acid, a bioactive endogenous substrate for mammalian glutathione transferase

Bull, A. W;
Seeley, S. K;
Geno, J;
Mannervik, B.

Biochimica Biophysica Acta ,2002, 1571, 77-82

Inactivation of carcinogenic diol epoxides of dibenzo [A,L]pyrene (dibenzo[DEF,P] chrysene) by human Alpha class glutathione transferases

Dreij, K;
Sundberg, K;
Jernström, B;
Johansson, A-S;
Mannervik, B;
Seidel, A.

Polycyclic Aromatic Compounds,
2002, 22, 823-829

Catalytic activities of human Alpha class glutathione transferases toward carcinogenic dibenzo[a,l] pyrene diol epoxides

Dreij, K;
Sundberg, K;
Johansson, A-S;
Nordling, E;
Seidel, A;
Persson, B;
Mannervik, B;
Jernström, B.
Chemical Research of Toxicology,
2002, 15, 825-831

Probing biomolecular interactions of glutathione transferase M2-2 by using peptide phage display

Edalat, M;
Pettersson, S;
Persson, M A A;
Mannervik, B.

ChemBioChem , 2002,3, 823-828

Screening for recombinant glutathione transferases active with monochlorobimane Eklund, B;
Edalat, M;
Stenberg, G;
Mannervik, B.
Analytical Biochemistry, 2002, 309, 102-108
Hybridization of Alpha class subunits generating a functional glutathione transferase A1-4 heterodimer Gustafsson, A;
Nilsson, L. O;
Mannervik, B.
J. of Molecular Biology, 2002, 316, 395-406
Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53 Hansson, LO;
Friedler, A;
Freund, S;
Rüdiger, S; Fersht AR.
Proceedings of the National Academy of Sciences of the United States of America , 2002, 16, 10305-10309
A statistical experimental design to study factors affecting enantioseparation of propranolol by capillary electrophoresis with cellobiohydrolase (Cel7A) as chiral selector Harang, V;
Tysk, M;
Westerlund, D;
Isaksson, R;
Johansson, G.
ELECTROPHORESIS , 2002, 23, 2306
Efficient docking of peptides to proteins without prior knowledge of the binding site Hetenyi, C;
van der Spoel, D.
PROTEIN SCIENCE, 2002, 11, 1729-1737
Identification of the catalytic triad in tripeptidyl- peptidase II trough site-directed mutagenesis Hibli, H;
Jozsa, E;
Tomkinson, B.
Biochimica et Biophysica Acta , 2002, 1601, 149-154
The cyclopentenone product of lipid peroxidation, 15A2t- isoprostane (8-iso- prostaglandin A2), is efficiently conjugated with glutathione by human and rat glutathione transferase A4-4 Hubatsch, I;
Mannervik, B;
Gao, L;
Roberts, J;
Chen, Y;
Morrow, J. D.
Chemical Research of Toxicology , 2002, 15, 1114-1118
Tetrapeptides as potent protease inhibitors of hepatitis C virus full-length NS3 (protease- helicase/NTPase) Johansson, A;
Poliakov, A;
Akerblom, E;
Lindeberg, G;
Winwarter, S;
Samuelsson, B;
Danielson, UH;
Hallberg, A.
BIOORGANIC & MEDICINAL CHEMISTRY, 2002, 12, 3915-3922
Active-site residues governing high steroid isomerase activity in human glutathione transferase A3-3 Johansson, A-S;
Mannervik, B.
J. of Biological Chemistry , 2002, 277, 16648-16654
The polymorphic human glutathione transferase T1-1, the most efficient glutathione transferase in the denitrosation and inactivation of the anticancer drug 1,3-bis (2-chloroethyl) -1-nitrosourea Lien, S;
Larsson, A-K;
Mannervik, B.
Biochemical Pharmacology , 2002, 63, 191-197
Relationships between structure and interaction kinetics for HIV-1 protease inhibitors Markgren, PO;
Schaal, W;
Hamalainen, M;
Karlen, A;
Hallberg, A;
Samuelsson, B;
Danielson, UH.
J. OF MEDICINAL CHEMISTRY , 2002, 25, 5430-5439
Relationships between structure and interaction kinetics for HIV-1 protease inhibitors Markgren, PO;
Schaal, W;
Hämäläinen, M;
Karlén, A;
Hallberg, A;
Samuelsson, B;
Danielson, UH.
J. OF MEDICAL CHEMISTRY , 2002, 3, 752
Inhibitioin of glutathione S-transferases by antimalarial drugs: possible implications for circumventing anticancer drug resistance Mukanganyama, S;
Widersten, M;
Yogeshkumar, S N;
Mannervik, B;
Hasler, J.
International Journal of Cancer, 2002, 97, 700-705
Aromatic residues in the C-terminal region of glutathione transferase A1-1 influence rate-determining steps in the catalytic mechanism Nilsson, L. O;
Edalat, M;
Pettersson, P. L;
Mannervik, B.
Biochimica Biophysica Acta , 2002, 1598, 199-205
Transmutation of human glutathione transferase A2-2 with peroxidase activity into an efficient steroid isomerase Pettersson, P. L;
Johansson, A-S;
Mannervik, B.
J. of Biological Chemistry , 2002, 277,30019-30022
Expression and purification of recombinant full-length NS3protease- helicase from a new variant of Hepatitis C virus protein Poliakov, A;
Hubatsch, I;
Shuman, C;
Stenberg, G;
Danielson, UH.
Protein Expr Purif , 2002, 25, 363-371
Cellobiose Quinone Oxidoreductase from the white rot fungus Phanerochaete chrysosporium is produced by intracellular proteolysis of Cellobiose Dehydrogenase Raices, M;
Montesino, R;
Cremata, J;
Szabó, I;
Henriksson, G;
Hallberg, B. M;
Pettersson, G;
Johansson, G.
Biochimica et Biophysica Acta: Gene Structure and expressi, 2002, 1576, 15-22
A semisyntetic glutathione peroxidase with high catalytic efficiency: Selenoglutathione transferase Ren, X;
Jemth, P;
Board, P;
Luo, G;
Mannervik, B;
Liu, J;
Zhang, K;
Shen, J.
Chemical Biology , 2002, 9, 789-794
Protein crystallography in a vapour stream: data collection, reaction initiation and intermediate trapping in naked hydrated protein crystals Sjögren, T;
Carlsson, G;
Larsson, G;
Hajdu, A;
Andersson, C;
Pettersson, H;
Hajdu, J.
J. OF APPLIED CRYSTALLOGRAPHY , 2002, 35 , 113-116
Synthesis and characterization of 6-chloroacetyl-2- dimethyl- aminonaphtalene as fluorogenic substrate and mechanistic probe for glutathione transferases Svensson, R;
Grenö, C;
Johansson, A-S;
Mannervik, B;
Morgenstern, R.
Analytical Biochemistry, 2002, 311, 171-178
The insert within the catalytic domain of tripeptidyl- peptidase II is important for the formation of the active complex Tomkinson, B;
Ni Laoi, B;
Wellington, K.
Eur. J. of Biochemistry, 2002, 269, 1438-1443
High-resolution capillary zone and gel electrophoresis of structurally similar amphipathic glutathione conjugates based on interaction with beta-cyclodextrins Végvári, Á;
Larsson, A-K;
Hjertén, S;
Mannervik, B.
ChemBioChem, 2002, 3, 1117-1125
Defining redox state of X-ray crystal structures by single-crystal ultraviolet-visible microspectro- photometry. Methods Wilmot, CM;
Sjögren, T;
Carlsson, GH;
Berglund, GI;
Hajdu, J.
ENZYMOLOGY, 2002, 353, 301-318
Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis Wray, C. J;
Tomkinson, B;
Robb, B. W;
Hasselgren, P-O.
Biochemical and Biophysical Research Communications, 2002, 1, 41-47
Immobilized- biomembrane affinity chromatography for binding studies of membrane proteins Gottschalk, I;
Lagerquist, C;
Zuo, S.-S;
Lundqvist, A;
Lundahl, P.
J Chromatogr. B., 2002, 768, 31-40
Glutathione peroxidase; Mannervik, B. Encyclopedia of Molecular Medicine, TE Creighton Ed , 2002
Glutathione transferase Mannervik, B. Encyclopedia of Molecular Medicine, TE Creighton Ed , 2002
Glyoxalases I and II Ridderström, M;
Mannervik, B.
Encyclopedia of Molecular Medicine, TE Creighton Ed , 2002
Well-known sugar transporters: the GLUT1 glucose transporter of human red blood cells and the glucose transporter and lactose permease of Escherichia coli Zuo, S.-S;
Lagerquist Hägglund, C;
Lundahl, P.
Recent Res. Devel. Biochem , 2002, 3, 527–546