Section of Chemistry : Dept. Biochemistry & Organic Chemistry :
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Dept. of Biochemistry & Organic Chemistry

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Publications 2003

Publications From biochemistry - 27 publications

 

Title Autor Journal/Year

Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors

Andersson, H.O;
Fridborg, K;
Löwgren, S;
Alterman, M;
Mühlman, A;
Björsne, M;
Garg, N;
Kvarnström, I;
Schaal, W;
Classon, B;
Karlén, A;
Danielson, U.H;
Ahlsén, G;
Nillroth, U;
Vrang, L;
Öberg, B;
Samuelsson, B;
Hallberg, A;
Unge, T.

European Journal of Biochemistry, 2003, 270, 170-1758

Kinetic and mechanistic analysis of the association and dissociation of inhibitors interacting with secreted aspartic acid proteases 1 and 2 from Candida albicans

Backman, D;
Danielson, U.H.

Biochimica et Biophysica Acta , 2003, 1646, 184-195

Selective recognition of peptide sequences by glutathione transferases: a possible mechanism for modulation of cellular stress-induced signaling pathways

Edalat, M;
Persson, M. A.A;
Mannervik, B.

Biological Chemistry, 2003, 384 , 645-651

Kinetic instability of p53 core domain mutants. Implications for rescue by small molecules

Friedler, A;
Veprintsev, D.B;
Hansson, L.O;
Fersht, A.R.

J Biol Chem, 2003, 26 , 24108-24112

Kinetic analysis of the interaction between HIV-1 protease and inhibitors in different buffer environments Gossas, T;
Danielson, U.H.
J. of Molecular Recognition ,
2003, 16 , 203-212

Improved lectin-mediated immobilization of human red blood cells in superporous agarose beads

Gottschalk, I;
Gustavsson, P-E;
Ersson, B;
Lundahl, P.

J. of Chromatography B ,
2003, 784, 203-208

Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenes to GSH adducts Hamilton, D. S;
Zhang, Xi;
Ding, Z;
Hubatsch, I;
Mannervik, B;
Houk, K.N;
Ganem, B;
Creighton, D. J.
J.of American Chemical Society ,
2003, 125, 15049-15058

Use of a fluorescence labelled, cellulose binding module from Phanerochaete chrysosporium Cel7D for studying wood cell wall ultrastructure

Hildén, L;
Daniel, G;
Johansson, G.

Biotechnology Letters ,2003, 25, 553-558

Profile - Stellan Hjertén, Uppsala University

Hjertén, S.

Analyst, 2003, 128, 1307-1309

Identification of residues in glutathione transferase capable of driving functional diversification in evolution - A novel approach to protein redesign

Ivarsson, Y;
Mackey, A. J;
Edalat, M;
Pearson, W. R;
Mannervik, B.
Journal of Biological Chemistry,
2003, 278, 8733-8738

Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-Length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals

Johansson, A;
Poliakov, A;
Akerblom, E;
Wiklund, K;
Lindeberg, G;
Winiwarter, S;
Danielson, UH;
Samuelsson, B;
Hallberg, A.

Bioorg Med Chem , 2003,11, 2551-2568

Migration time and peak area artifacts caused by systemic effects in voltage controlled capillary electrophoresis Johansson, G;
Isaksson, R;
Harang, V.
J. of Chromatography A , 2003, 1004, 91-98
Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human GSTP1-1 Kong, G. K.-W;
Polekhina, G;
Mckinstry, W.J;
Parker, M.W;
Dragani, B;
Aceto, A;
Paludi, D;
Rossi Principe, D;
Mannervik, B;
Stenberg, G.
J. of Biological Chemistry , 2003, 278, 1291-1302
Centrifugal and chromatographic analyses of tryptophan and tyrosine uptake by red blood cells and GLUT1 proteoliposomes with permeability estimates and observations on dihydrocytochalasin B Lagerquist Hägglund, C;
Lundahl, P.
J. Biochem. Biophys. Methods , 2003, 2, 127-140
Refolding of a recombinant full-length non-structural (NS3) protein from hepatitis C virus by chromatographic procedures Li, M;
Poliakov, A;
Danielson, U. H;
Su, Z;
Janson, J-C.
Biotechnology Letters , 2003, 20, 1729-1734
Naturally-occurring Phe151Leu substitution near a conserved folding module lowers stability of glutathione transferase P1-1 Lin, H. J;
Johansson, A-S;
Stenberg, G;
Materi, A. M;
Park, J. M;
Dai, A;
Zhou, H;
Gim, J. S.Y;
Kau, I. H; Hardy
Steven, I;
Parker, M. W;
Mannervik, B.
Biochimica Biophysica Acta , 2003, 1649, 16-23
Novel polymorphisms in the glutathione transferase superfamily Mannervik, B. Pharmacogenetics (editorial), 2003, 13, 127-128
Peptide-based inhibitors of hepatitis C virus full-length NS3(protease-helicase/NTPase): model compounds towards small molecule inhibitors. Oscarsson, K;
Poliakov, A;
Oscarson, S;
Danielson, UH;
Hallberg, A;
Samuelsson, B.
Bioorg Med Chem , 2003, 11, 2955-2963
Mild two-step conversion of primary amides to alcohols by reduction of acylimidodicarbonates with sodium borohydride Ragnarsson, U;
Grehn, L;
Monteiro, L.S;
Maia, H.
Synlett , 2003, 15, 2386-2388
Elucidation of HIV-1 protease resistance by characterization of interaction kinetics between inhibitors and enzyme variants Shuman, C.F;
Markgren, P.-O;
Hämäläinen, M;
Danielson, U.H.
Antiviral Research , 2003,58, 235-242
Synergistic cellulose hydrolysis can be described in terms of fractal like kinetics Väljamäe, P;
Kipper, K;
Pettersson, G;
Johansson, G.
Biotechnology and Bioengineering , 2003, 2, 254-257
Hybrid microdevice electrophoresis of peptides, proteins, DNA, viruses and bacteria in various separation media, using UV-detection Végvári, Á;
Hjertén, S.
Electrophoresis , 2003, 20, 3479-3486
Effects of acidic media pre-incubation on flax enzyme retting efficiency Zhang, J;
Johansson, G;
Pettersson, B;
Akin, D. E;
Foulk, J. A;
Khalili, S;
Henriksson, G.
Textile Research Journal , 2003, 3, 263-267
On the oligomeric state of the red blood cell glucose transporter GLUT1 Zuo, S;
Hellman, U;
Lundahl, P.
Biochimica et Biophysica Acta, 2003, 1618, 8-16
Interaction of drugs with liposomes and proteoliposomes Engvall, C;
Lundahl, P.
Affinity capillary electrophoresis in pharmaceutics and biopharmaceutics, 2003, , 151-173
Exploring the functional space of combinatorial mutant libraries for the directed evolution of novel enzyme activities Mannervik, B; Hansson, L.O;
Bardsley, W.G.
Enzyme Functionality: Design, Engineering and Screening , 2003, ,443-460
Combinbatorial approaches to the evolutionary redesign of substrate selectivities of glutathione transferases Mannervik, B;
Larsson, A-K;
Hansson, L.
Drug Metabolism , 2003, 35, 16